Endocrine Abstracts

Case: A 77-year-old man was admitted with a pathological fracture of the right femur, which required intramedullary nailing. He had previously been diagnosed with Paget’s disease affecting the right femur and also hyperparathyroidism with a large parathyroid adenoma on Sestamibi scan which had been managed at another hospital. On this admission, his corrected calcium was 2.79 (2.15–2.55) mmol/l, PTH 643 (15–65) pg/ml and alkaline phosphatase 258 (30–130) U/...

Introduction: Craniopharyngiomas are usually benign intracranial tumours which can sometimes be locally aggressive. Malignant transformation is extremely rare and has a poor prognosis. We report a case of a patient who developed carcinomatous changes in a craniopharyngioma which was first excised almost 55 years ago.Case report: Mr AM was diagnosed with a craniopharyngioma at the age of 5 years. He underwent surgery in 1952 but was lost to follow up and ...

Non-functioning pituitary macroadenomas (NFPAs) are commonly associated with headaches, visual deficits and hypopituitarism. Urgent transsphenoidal surgery (TSS) should be considered for all patients presenting with visual compromise. We evaluated outcomes in 65 patients with NFPAs undergoing TSS in our unit. Patients who had undergone previous pituitary surgery or prior radiotherapy were excluded from this evaluation, as were those with classical pituitary apoplexy and predom...